Uralenol
Uralenol is a natural PTP1B inhibitor (IC50=21. 5 μM) from Broussonetia papyrifera. PTP1B have been shown to play a major role in the dephosphorylation of the insulin receptor in many cellular and biochemical studies[1].
Product Specifications
CAS Number
[139163-15-8]
UNSPSC
12352005
Target
Phosphatase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/uralenol.html
Purity
99.12
Solubility
DMSO : ≥ 50 mg/mL
Smiles
O=C1C(O)=C(C2=CC(C/C=C(C)\C)=C(O)C(O)=C2)OC3=CC(O)=CC(O)=C13
Molecular Formula
C20H18O7
Molecular Weight
370.35
References & Citations
[1]Chen RM, et al. Natural PTP1B inhibitors from Broussonetia papyrifera. Bioorg Med Chem Lett. 2002;12 (23) :3387-3390.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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