MX69-102
Product Specifications
UNSPSC Description
MX69-102 (compound MX69-102) is an MDM-2/p53 inhibitor, inducing MDM2 degradation, resulting in p53 activation and cancer cell apoptosis. MX69-102 shows effective inhibition on xenografted human MDM2-overexpressing ALL in SCID mice.[1].
Target Antigen
MDM-2/p53
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mx69-102.html
Smiles
O=C(C1=CC=CC(NS(=O)(C2=CC=C(C3=C2)NC([C@H]4[C@@H]3OCC4)C5=CC=C(C=C5)C(C(C)C)=O)=O)=C1)C
Molecular Weight
518.62
References & Citations
[1]Liu T, et al. An MDM2 degrader shows potent cytotoxicity to MDM2-overexpressing acute lymphoblastic leukemia cells with minimal toxicity to normal cells/tissues. Cancer Lett. 2024 Aug 28;598:217126.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-169240/MX69-102-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-169240/
Clinical Information
No Development Reported
Curated Selection
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