(Rac)-S 16924
Product Specifications
UNSPSC Description
(Rac)-S 16924 is a partial agonist of the 5-HT1A receptor. (Rac)-S 16924 regulates signaling through its interaction with the 5-HT1A receptor, and (Rac)-S 16924 can stabilize the receptor in its G-protein-coupled conformation without fully activating it, which may affect intracellular signaling pathways associated with this receptor. (Rac)-S 16924 can be used to study the 5-HT1A receptor in mental disorders, especially schizophrenia[1].
Target Antigen
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/rac-s-16924.html
Smiles
FC1=CC=C(C=C1)C(CC2CN(CC2)CCOC3=C4OCCOC4=CC=C3)=O
Molecular Weight
385.43
References & Citations
[1]Newman-Tancredi A, et al. Efficacy of antipsychotic agents at human 5-HT1A receptors determined by [3H] WAY100, 635 binding affinity ratios: relationship to efficacy for G-protein activation[J]. European journal of pharmacology, 2001, 428(2): 177-184.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-106964A/Rac-S-16924-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-106964A/
Clinical Information
No Development Reported
CAS Number
734513-52-1
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