NTNCB (hydrochloride)
NTNCB (Compound 11) hydrochloride is a potent and selective neuropeptide Y Y5 (NPY Y5) receptor antagonist with a Ki of 8 nM against human Y5[1].
Product Specifications
CAS Number
[191931-56-3]
UNSPSC
12352005
Target
Neuropeptide Y Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ntncb-hydrochloride.html
Purity
98.36
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=S(C1=CC=CC=C1[N+]([O-])=O)(NC[C@H]2CC[C@H](CNCC3CC4=C(C=CC=C4)CC3)CC2)=O.[H]Cl
Molecular Formula
C25H34ClN3O4S
Molecular Weight
508.07
References & Citations
[1]Islam I, et al. Discovery of potent and selective small molecule NPY Y5 receptor antagonists. Bioorg Med Chem Lett. 2002 Jul 8;12 (13) :1767-9.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NPY Y1 receptor; NPY Y5 receptor
Available Sizes
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