Lufenuron

Lufenuron is an orally active lipophilic benzoylurea insecticide and a chitin synthesis inhibitor that can used for flea and fish lice control. Lufenuron inhibits moulting of arthropods. Lufenuron induces reproductive toxicity, genotoxic effects and oxidative stresses in pregnant albino rats and their fetuses[1][2][3][4].

Product Specifications

CAS Number

[103055-07-8]

Product Name Alternative

TNF Protease Inhibitor 2

UNSPSC

12352005

Hazard Statement

H317, H330, H410

Target

Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/lufenuron.html

Purity

99.57

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(NC(NC1=CC(Cl)=C(OC(F)(F)C(F)C(F)(F)F)C=C1Cl)=O)C2=C(F)C=CC=C2F

Molecular Formula

C17H8Cl2F8N2O3

Molecular Weight

511.15

Precautions

H317, H330, H410

References & Citations

[1]T C M Brock, et al. Toxicity of Sediment-Bound Lufenuron to Benthic Arthropods in Laboratory Bioassays. Aquat Toxicol. 2018 May;198:118-128.|[2]Cai Wang, et al. Lufenuron Suppresses the Resistance of Formosan Subterranean Termites (Isoptera: Rhinotermitidae) to Entomopathogenic Bacteria. J Econ Entomol. 2013 Aug;106 (4) :1812-8.|[3]Basal WT, et al. Lufenuron induces reproductive toxicity and genotoxic effects in pregnant albino rats and their fetuses. Sci Rep. 2020 Nov 11;10 (1) :19544.|[4]Ghazawy N. Ultrastructural observations on the gonads and neurosecretory cells of schistocerca gregaria after treatment with Lufenuron (CGA-184699) [J]. Journal of Orthoptera Research, 2012, 21 (2) : 141-148.