CD8A antibody
Product Specifications
Background
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms
T-cell surface glycoprotein CD8 alpha chain|T-lymphocyte differentiation antigen T8/Leu-2|CD8A|MAL
Gene ID
925
UniProt
P01732
Host
Mouse
Reactivity
Human
Immunogen
CD8a molecule
Target
CD8A
Clonality
Monoclonal
Isotype
IgG1
Applications
ELISA, WB, IHC
Purification
Protein A+G purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:500 - 1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
30 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
2B9
Tested Applications
ELISA, WB, IHC
Curated Selection
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