PB089

PB089 is a Drug-liker containing a PEG unit and a cleavable linker attached to Exatecan[1].

Product Specifications

CAS Number

[2892336-54-6]

UNSPSC

12352203

Target

Drug-Linker Conjugates for ADC

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pb089.html

Purity

99.98

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(OCC(C=C1)=CC=C1NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC([C@H](CCCCNC(CCOCCOCCOCCOCCOCCOCCOCCOCCN(C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)NC(CCCCCN(C2=O)C(C=C2)=O)=O)=O)=O)=O)N[C@@H]3C(C4=C5CC3)=C(CN6C7=CC([C@@]8(O)CC)=C(COC8=O)C6=O)C7=NC4=CC(F)=C5C

Molecular Formula

C90H133FN12O32

Molecular Weight

1914.08

References & Citations

[1]Xiao, S, et, al. Linkers, drug linkers and conjugates thereof and methods of using the same. WO2023280227A2.|[2]Xiao, S, et, al. Linkers, drug linkers and conjugates thereof and methods of using the same. WO2023280227A2.