5-Aminothalidomide
5-Aminothalidomide is an E3 ligase ligand used in PROTAC technology. 5-Aminothalidomide can be used to synthesize various PROTACs, such as the PROTAC BRD9 Degrader-7 (HY-155361) .
Product Specifications
CAS Number
[191732-76-0]
UNSPSC
12352200
Hazard Statement
H301, H312, H360
Target
Ligands for E3 Ligase
Type
Biochemical Assay Reagents
Related Pathways
PROTAC
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/5-aminothalidomide.html
Purity
99.69
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
C1(N(C(C=2C=C(C=CC12)N)=O)C3C(NC(CC3)=O)=O)=O
Molecular Formula
C13H11N3O4
Molecular Weight
273.25
Precautions
H301, H312, H360
References & Citations
[1]Vicente ATS, et al. Synthesis, biological evaluation and clinical trials of Cereblon-based PROTACs. Commun Chem. 2025 Jul 29;8 (1) :218.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Available Sizes
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