(E) -SI-2

(E) -SI-2 is an isomer of SI-2, an inhibitor of the steroid receptor coactivator SRC-3. SI-2 has anticancer activity and increases the number of cytotoxic immune cells in mice with breast cancer[1].

Product Specifications

CAS Number

[380537-35-9]

Product Name Alternative

(E) -EPH 116

UNSPSC

12352005

Hazard Statement

H315-H319

Target

Drug Isomer

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/e-si-2.html

Solubility

10 mM in DMSO

Smiles

CN1C2=CC=CC=C2N=C1N/N=C(C3=CC=CC=N3)\C

Molecular Formula

C15H15N5

Molecular Weight

265.31

Precautions

P264-P280-P302+P352-P305+P351+P338-P362+P364

References & Citations

[1]Han SJ, et al. Steroid receptor coactivator-3 inhibition generates breast cancer antitumor immune microenvironment. Breast Cancer Res. 2022 Oct 31;24 (1) :73.