Bis-PEG6-acid

Bis-PEG6-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

[119189-70-7]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bis-peg6-acid.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

OC(CCOCCOCCOCCOCCOCCOCCC(O)=O)=O

Molecular Formula

C16H30O10

Molecular Weight

382.40

Precautions

H302, H315, H319, H335

References & Citations

[1]Zorba A, et al. Delineating the role of cooperativity in the design of potent PROTACs for BTK. Proc Natl Acad Sci U S A. 2018 Jul 31;115 (31) :E7285-E7292.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PEG Linkers

Available Sizes

Curated Selection

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