Sodium new houttuyfonate
Product Specifications
UNSPSC Description
Sodium new houttuyfonate (SNH) is a partially reversible NDM-1 inhibitor with an IC50 of 14.2 μM. Sodium new houttuyfonate is an inhibitor against renin and angiotensin I converting enzyme (ACE). Sodium new houttuyfonate can recover the antibacterial activity of Meropenem (HY-13678) against E. coli BL21/pET15b-blaNDM-1[1].
Target Antigen
Bacterial; Renin
Type
Natural Products
Related Pathways
Anti-infection;Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sodium-new-houttuyfonate.html
Solubility
10 mM in DMSO
Smiles
O=S(C(O)CC(CCCCCCCCCCC)=O)(O[Na])=O
Molecular Weight
330.42
References & Citations
[1]Lifang Wang, et al. Novel partially reversible NDM-1 inhibitors based on the naturally occurring houttuynin. Bioorg Chem. 2024 Apr 3:147:107328.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N12763/Sodium-new-houttuyfonate-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N12763/
Clinical Information
No Development Reported
CAS Number
112714-99-5
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