Pinocembrin chalcone
Product Specifications
UNSPSC Description
Pinocembrin chalcone (2',4',6'-Trihydroxychalcone) is an antibacterial compound from Helichrysum Trilineatum. Pinocembrin chalcone facilitates AMP-activated protein kinase (AMPK) activation, improves glucose tolerance, increases muscle FAO and reduces fat accumulation in the liver and skeletal muscles in high-fat diet-induced (HFD) diabetic mice. Pinocembrin chalcone is promising for research of gastric ulcers and diabetes[1][2].
Target Antigen
AMPK; Bacterial
Type
Natural Products
Related Pathways
Anti-infection;Epigenetics;PI3K/Akt/mTOR
Applications
COVID-19-immunoregulation
Field of Research
Infection; Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pinocembrin-chalcone.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(O)C=C(O)C=C1O)/C=C/C2=CC=CC=C2
Molecular Weight
256.25
References & Citations
[1]P D Bremner, et al. Pinocembrin Chalcone: An Antibacterial Compound From Helichrysum Trilineatum. Planta Med. 1998 Dec;64(8):777.|[2]Shin J, et al. Antidiabetic effects of trihydroxychalcone derivatives via activation of AMP-activated protein kinase[J]. Journal of Industrial and Engineering Chemistry, 2018, 60: 177-184.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N7515/Pinocembrin-chalcone-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N7515/Pinocembrin-chalcone-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
4197-97-1
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