6′SLN

6′SLN is a cancer-related extracellular vesicle (EVs) surface glycan that serves as a key form of protein glycosylation in EVs. 6′SLN is also a sialic acid derivative that can interact with hemagglutinins (HAs) from human and avian influenza virus strains, making it useful for research into anti-influenza drugs[1][2].

Product Specifications

CAS Number

[64364-50-7]

Product Name Alternative

Neu5Acα2-6Galβ1-4GlcNAc

UNSPSC

12352211

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/6-sln.html

Purity

99.87

Solubility

DMSO : 50 mg/mL (ultrasonic) |H2O : 125 mg/mL (ultrasonic)

Smiles

OC[C@@H](O[C@H]([C@@H]([C@H]1O)NC(C)=O)O)[C@H]1O[C@@H]([C@@H]([C@H]([C@H]2O)O)O)O[C@@H]2CO[C@]3(O[C@@]([C@@H]([C@H](C3)O)NC(C)=O)([H])[C@H](O)[C@H](O)CO)C(O)=O

Molecular Formula

C25H42N2O19

Molecular Weight

674.60

References & Citations

[1]Jiang Z, et al. An Electrochemiluminescent Sensor Based on Glycosyl Imprinting and Aptamer for the Detection of Cancer-Related Extracellular Vesicles. Anal Chem. 2024 Feb 13;96 (6) :2550-2558.|[2]Vasile F, et al. NMR interaction studies of Neu5Ac-α- (2,6) -Gal-β- (1-4) -GlcNAc with influenza-virus hemagglutinin expressed in transfected human cells. Glycobiology. 2018 Dec 1;28 (1) :42-49.