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Fenquizone

Fenquizone (MG-13054) is an orally active diuretic. Fenquizone acts primarily on the diluting segment of the nephron cortex, similar to thiazide diuretics. Fenquizone demonstrates diuretic and natriuretic potency and duration of action comparable to thiazide diuretics but weaker than loop diuretics.​ Fenquizone reduces CH₂O without affecting TCH₂O, does not increase calcium/phosphate excretion, and has no loop or collecting duct effects. Fenquizone is used in the study of edema and hypertension[1].

Product Specifications

CAS Number

[20287-37-0]

Product Name Alternative

MG-13054

UNSPSC

12352005

Target

Potassium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cardiovascular Disease; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/fenquizone.html

Purity

99.58

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=S(C1=CC2=C(NC(C3=CC=CC=C3)NC2=O)C=C1Cl)(N)=O

Molecular Formula

C14H12ClN3O3S

Molecular Weight

337.78

References & Citations

[1]Ferrando C, et al. On the pharmacological actions of a diuretic, fenquizone, with particular reference to its site of action. J Pharm Pharmacol. 1981 Apr;33 (4) :219-22.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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