Glycodeoxycholate (Sodium)

Glycodeoxycholate Sodium (Sodium glycyldeoxycholate) is a bile salt. Glycodeoxycholate Sodium has cytotoxicity to cancer cell, changes the permeability of the pancreatic duct and decreases glucose levels[1][2][3].

Product Specifications

CAS Number

[16409-34-0]

Product Name Alternative

Sodium glycyldeoxycholate

UNSPSC

12352211

Hazard Statement

H302, H312, H332

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/Glycodeoxycholate_Sodium.html

Purity

99.92

Solubility

DMSO : 125 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 100 mg/mL (ultrasonic)

Smiles

O=C(O[Na])CNC(CC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@]12C)=O

Molecular Formula

C26H42NNaO5

Molecular Weight

471.61

Precautions

H302, H312, H332

References & Citations

[1]Brayden DJ, et al. Sodium glycodeoxycholate and sodium deoxycholate as epithelial permeation enhancers: in vitro and ex vivo intestinal and buccal bioassays. Eur J Pharm Sci. 2021 Apr 1;159:105737.|[2]Farmer RC, et al. Effects of bile salts on permeability and morphology of main pancreatic duct in cats. Dig Dis Sci. 1984 Aug;29 (8) :740-51. |[3]Illum L, et al. Bioadhesive starch microspheres and absorption enhancing agents act synergistically to enhance the nasal absorption of polypeptides. Int J Pharm. 2001 Jul 3;222 (1) :109-19.