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CD34 Monoclonal Antibody

Product Specifications

Background

CD34, also known as gp105-120, is a type I monomeric sialomucin-like glycophosphoprotein with an approximate molecular weight of 105-120 kD. Selectively expressed on the majority of hematopoietic stem/progenitor cells, bone marrow stromal cells, capillary endothelial cells, embryonic fibroblasts, and some nervous tissue, CD34 is a commonly used marker to identify human hematopoietic stem/progenitor cells. According to the differential sensitivity to enzymatic cleavage, four groups of epitopes of CD34 have been described. CD34 mediates cell adhesion and lymphocytes homing through binding to L-selectin and E-selectin ligands.

Abbreviation

CD34

UniProt

P28906

Host

Mouse

Reactivity

Human

Immunogen

Full length human CD34 expression plasmid

Target

GIG; MORT; Hematopoietic progenitor cell antigen CD; Gp105; CD34; CD34 molecule; GIG3; MORT1; Gp105-120; My10; Hematopoietic progenitor cell antigen CD34; Mucosialin; CD34; CD34 molecule; GIG3; MORT1; RP11-328D5.2

Clonality

Monoclonal

Clone

6C6

Conjugation

Unconjugated

Applications

IHC-P

Field of Research

Neuroscience; Immunology; Stem Cells; Cancer; Cardiovascular; Developmental Biology

Purification

Protein A

Concentration

1 mg/mL

Dilution

IHC-P 1:30-1:100

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Isotype

IgG1

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