CD34 Monoclonal Antibody
Product Specifications
Background
CD34, also known as gp105-120, is a type I monomeric sialomucin-like glycophosphoprotein with an approximate molecular weight of 105-120 kD. Selectively expressed on the majority of hematopoietic stem/progenitor cells, bone marrow stromal cells, capillary endothelial cells, embryonic fibroblasts, and some nervous tissue, CD34 is a commonly used marker to identify human hematopoietic stem/progenitor cells. According to the differential sensitivity to enzymatic cleavage, four groups of epitopes of CD34 have been described. CD34 mediates cell adhesion and lymphocytes homing through binding to L-selectin and E-selectin ligands.
Abbreviation
CD34
UniProt
P28906
Host
Mouse
Reactivity
Human
Immunogen
Full length human CD34 expression plasmid
Target
GIG; MORT; Hematopoietic progenitor cell antigen CD; Gp105; CD34; CD34 molecule; GIG3; MORT1; Gp105-120; My10; Hematopoietic progenitor cell antigen CD34; Mucosialin; CD34; CD34 molecule; GIG3; MORT1; RP11-328D5.2
Clonality
Monoclonal
Clone
6C6
Conjugation
Unconjugated
Applications
IHC-P
Field of Research
Neuroscience; Immunology; Stem Cells; Cancer; Cardiovascular; Developmental Biology
Purification
Protein A
Concentration
1 mg/mL
Dilution
IHC-P 1:30-1:100
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Isotype
IgG1
Curated Selection
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