XT-1

XT-1 is an antimicrobial peptide derived from skin secretions of Xenopus tropicalis. XT-1 has strong activity against S.aureus, E.coli and C.albicans, the vaule of MIC are 5, 6, 50 μM , respectively[1].

Product Specifications

CAS Number

[398143-78-7]

UNSPSC

12352209

Target

Bacterial

Type

Peptides

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/xt-1.html

Solubility

10 mM in DMSO

Smiles

O=C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(C)C)C(NCC(N2[C@@H](CCC2)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](CCCCN)C(NCC(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H]([C@@H](C)CC)C(N3[C@@H](CCC3)C(N[C@@H](CC4=CNC=N4)C(N[C@@H](CC(C)C)C(N[C@@H]([C@@H](C)CC)C(N5[C@@H](CCC5)C(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(N)=O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CN

Molecular Formula

C134H227N37O31

Molecular Weight

2852.47

References & Citations

[1]Ali MF, et al. Antimicrobial peptides isolated from skin secretions of the diploid frog, Xenopus tropicalis (Pipidae) . Biochim Biophys Acta. 2001 Nov 26;1550 (1) :81-9.