(S)-BAY 2965501
Product Specifications
UNSPSC Description
(S)-BAY 2965501 is the left-handed isomer of BAY 2965501 (HY-153343). BAY 2965501 is a potent and selective diacylglycerol kinase zeta (DGKζ) inhibitor. BAY 2965501 induces pERK activation. BAY 2965501 can be used for the research of cancer[1].
Target Antigen
DGK; ERK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway;Metabolic Enzyme/Protease;Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/s-bay-2965501.html
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
NC([C@H](C)N(C1=CC=C(C=C1)F)C2=NC(N)=C(C(C3=CC=C(C=C3)OC)=O)S2)=O
Molecular Weight
414.45
References & Citations
[1]Schubert N, et al. Phosphorylated extracellular signal-regulated kinase (pERK) activation in T effector cells as a target engagement biomarker for the DGK味 inhibitor BAY2965501 in clinical trials. Cancer Research, 2023, 83(7_Supplement): 2116-2116.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-153343A/S-BAY-2965501-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-153343A/S-BAY-2965501-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2732902-09-7
Available Sizes
Curated Selection
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