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Uric acid

Product Specifications

UNSPSC Description

Uric acid, scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric acid can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation[1][2].

Target Antigen

Endogenous Metabolite; Reactive Oxygen Species

Type

Natural Products

Related Pathways

Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/Uric_acid.html

Purity

99.96

Solubility

1M NaOH : 8.33 mg/mL (ultrasonic;warming;adjust pH to 12 with 1M NaOH;heat to 60°C)|DMSO : < 1 mg/mL (ultrasonic)|H2O : 6.25 mg/mL (ultrasonic;adjust pH to 10 with 1M NaOH)

Smiles

O=C(N1)NC2=C(NC(N2)=O)C1=O

Molecular Weight

168.11

References & Citations

[1]Yasutake Y, et al. Uric acid ameliorates indomethacin-induced enteropathy in mice through its antioxidant activity. J Gastroenterol Hepatol. 2017 Nov;32(11):1839-1845.|[2]Wang Q, et al. Recent Progress on Uric Acid Detection: A Review. Crit Rev Anal Chem. 2020;50(4):359-375.BMC Neurol. 2023 Dec 16;23(1):444.|Cell Rep Med. 2024 Aug 20;5(8):101690.|Drug Dev Res. 2020 Nov;81(7):859-866.|Exp Biol Med. 2021 Oct 4;15353702211047183.|Int J Mol Sci. 2022 Jun 20;23(12):6860.|J Hazard Mater. 2024 Sep 23:480:135938.|Nature. 2024 Dec 18.|Research Square Preprint. 2022 Feb.|Research Square Preprint. 2023 Jul 28.|Arab J Chem. 2024 Jul 20.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-B2130/Uric-acid-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-B2130/Uric-acid-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

69-93-2

Available Sizes

Curated Selection

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