S-5751
Product Specifications
UNSPSC Description
S-5751 is an orally active prostaglandin DP receptor antagonist. S-5751 inhibits cAMP generation in platelet-rich plasma induced by PGD2 with IC50 0.12 μM. S-5751 has anti-inflammatory activity. S-5751 can be used in asthma research[1].
Target Antigen
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/s-5751.html
Solubility
10 mM in DMSO
Smiles
O=C(C(C1=C2)=CSC1=CC=C2O)N[C@H]3[C@@]4([H])C(C)([C@](C[C@@H]3C/C=C\CCCC(O)=O)([H])C4)C
Molecular Weight
441.58
References & Citations
[1]Shichijo M, et al. A prostaglandin D2 receptor antagonist modifies experimental asthma in sheep. Clin Exp Allergy. 2009 Sep;39(9):1404-14.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-19755/S-5751-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-19755/
Clinical Information
Phase 2
CAS Number
209268-36-0
Curated Selection
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