Onitin
Onitin is a natural product, that can be isolated from Onychium siliculosum. Onitin is also a non-competitive antagonist of histamine. Onitin shows activity in blocking the peristaltic reflex of the guinea-pig ileum, in inhibition of the responses of guinea-pig ileum to histamine and of inhibition of the responses of guinea-pig tracheal muscle to histamine[1].
Product Specifications
CAS Number
[53823-02-2]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Histamine Receptor
Type
Natural Products
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/onitin.html
Solubility
10 mM in DMSO
Smiles
CC1=C(CCO)C(C)=C(O)C(CC2(C)C)=C1C2=O
Molecular Formula
C15H20O3
Molecular Weight
248.32
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Wu T S, et al. Flavanone and other constituents from Onychium siliculosum. Phytochemistry, 1981, 20 (3) :527–529.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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