Disitamab

Disitamab (RC48-0) is a humanized monoclonal antibody targeting HER2. Disitamab can be used in the synthesis of antibody-drug conjugates (ADCs), Disitamab vedotin (HY-P9985) [1].

Product Specifications

CAS Number

[2185868-98-6]

Product Name Alternative

RC48-0

UNSPSC

12352203

Target

ADC Antibody; EGFR

Type

Inhibitory Antibodies

Related Pathways

Antibody-drug Conjugate/ADC Related; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/disitamab.html

Purity

98.70

Solubility

10 mM in DMSO

Smiles

[Disitamab]

Molecular Weight

(144.16 kDa)

References & Citations

[1]Jiang J, et al. Preclinical safety profile of disitamab vedotin: a novel anti-HER2 antibody conjugated with MMAE. Toxicol Lett. 2020;324:30-37.

Shipping Conditions

Dry Ice

Storage Conditions

Store at -80°C for 2 years

Scientific Category

Inhibitory Antibodies

Clinical Information

Phase 4

Isoform

ErbB2/HER2

Available Sizes

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