CGAMP (diammonium)
CGAMP (Cyclic GMP-AMP) diammonium functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. cGAMP diammonium activates stimulator of interferon genes (STING), which activates a signaling cascade leading to the production of type I interferons and other immune mediators[1][2][3][4].
Product Specifications
Product Name Alternative
Cyclic GMP-AMP (diammonium) ; 3',3'-cGAMP (diammonium)
UNSPSC
12352005
Target
Endogenous Metabolite; STING
Type
Natural Products
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cgamp-diammonium.html
Purity
96.63
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
O=P(O[C@H]1[C@@H](O)[C@H](N2C=NC3=C2N=CN=C3N)O[C@@H]1COP4(O)=O)(O)OC[C@@H]5[C@@H](O4)[C@@H](O)[C@H](N6C=NC7=C6N=C(N)NC7=O)O5.N.N
Molecular Formula
C20H30N12O13P2
Molecular Weight
708.47
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite
Available Sizes
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