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rac-MF-094

Product Specifications

UNSPSC Description

rac-MF-094 is the racemic mixture of MF-094 (HY-112438). MF-094 is a potent and selective USP30 inhibitor with an IC50 of 120 nM. MF-094 increases protein ubiquitination and accelerates mitophagy[1].

Target Antigen

Deubiquitinase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/rac-mf-094.html

Smiles

O=C(C(CC1=CC=CC=C1)NC(C2CCCCC2)=O)NC3=CC=CC4=C(S(=O)(NC(C)(C)C)=O)C=CC=C43

Molecular Weight

535.70

References & Citations

[1]Kluge AF, et al. Novel highly selective inhibitors of ubiquitin specific protease 30 (USP30) accelerate mitophagy. Bioorg Med Chem Lett. 2018 Aug 15;28(15):2655-2659.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-112438A/rac-MF-094-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-112438A/

Clinical Information

No Development Reported

CAS Number

2758431-95-5

Curated Selection

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