F092
F092 is an inhibitor of hematopoietic prostaglandin D synthase (H-PGDS) with a KD value of 0.14 nM. F092 can be used in the study of allergic and inflammatory responses[1].
Product Specifications
CAS Number
[2250261-59-5]
UNSPSC
12352005
Target
PGE synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/f092.html
Purity
99.79
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(C1=CN=C(C2=NC=CC=C2)N=C1)NC3=CC=C(N4C(CCC4)=O)C=C3
Molecular Formula
C20H17N5O2
Molecular Weight
359.38
References & Citations
[1]Takaya D, et al. Characterization of crystal water molecules in a high-affinity inhibitor and hematopoietic prostaglandin D synthase complex by interaction energy studies[J]. Bioorganic & Medicinal Chemistry, 2018, 26 (16) : 4726-4734.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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