Tibenelast sodium

Tibenelast sodium is a phosphodiesterase inhibitor.

Product Specifications

CAS Number

[105102-18-9]

Product Name Alternative

LY 186655

UNSPSC

12352005

Target

Phosphodiesterase (PDE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Tibenelast_(sodium).html

Purity

99.66

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(C1=CC2=CC(OCC)=C(OCC)C=C2S1)[O-].[Na+]

Molecular Formula

C13H13NaO4S

Molecular Weight

288.29

References & Citations

[1]Schwertschlag US, et al. Effect of tibenelast (a phosphodiesterase inhibitor) and theophylline on isoproterenol-stimulated heart rate, cyclic AMP and norepinephrine levels. Pharmacology. 1993;46 (3) :142-7.|[2]Ho PP, et al. Tibenelast, 5,6-diethoxybenzo (B) thiophene-2-carboxylic acid, sodium salt (LY186655), is an orally active anti-asthma compound in the guinea pig. Life Sci. 1990;46 (13) :917-25.