Claramine (TFA)

Claramine TFA is a steroidal polyamine. Claramine TFA can regulate the properties of lipid membranes and protect cells from various biological toxins, including misfolded protein oligomers and toxins derived from biological proteins[1].

Product Specifications

CAS Number

[3030428-57-7]

UNSPSC

12352211

Target

Phosphatase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/claramine-tfa.html

Purity

99.96

Solubility

DMSO : 120 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

C[C@@]12[C@]3([H])[C@](C[C@H](C1([H])C[C@H](CC2)O)NCCCNCCCCNCCCN)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)CCCC(C)C)C.OC(C(F)(F)F)=O

Molecular Formula

C39H73F3N4O3

Molecular Weight

703.02

References & Citations

[1]Kreiser RP, et al. A Brain-Permeable Aminosterol Regulates Cell Membranes to Mitigate the Toxicity of Diverse Pore-Forming Agents. ACS Chem Neurosci. 2022;13 (8) :1219-1231.