G12D ligand 1
Product Specifications
UNSPSC Description
G12D ligand 1 is a Ligand for Target Protein for PROTAC. G12D ligand 1 can be used to synthesize Setidegrasib (HY-148273)[1].
Target Antigen
Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/g12d-ligand-1.html
Smiles
OC1=C(C2=C(C=NN3)C3=CC(F)=C2C)C(C4CC4)=CC(C(N5[C@@](CN6)([H])C[C@@]6([H])C5)=N7)=C1N=C7OC8CCOCC8
Molecular Weight
530.59
References & Citations
[1]Yoshinari Tomohiro, et al. Quinazoline compound for inducing degradation of g12d-mutation kras protein. WO2022173032A1. 2022 August 18.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-168700/G12D-ligand-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-168700/
Clinical Information
No Development Reported
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