Pectolinarigenin
Pectolinarigenin is a dual inhibitor of COX-2/5-LOX. Anti-inflammatory activity[1]. Pectolinarigenin has potent inhibitory activities on melanogenesis[2].
Product Specifications
CAS Number
[520-12-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
COX; Lipoxygenase
Type
Natural Products
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pectolinarigenin.html
Purity
99.79
Solubility
DMSO : 33.33 mg/mL (ultrasonic)
Smiles
O=C1C=C(C2=CC=C(OC)C=C2)OC3=CC(O)=C(OC)C(O)=C13
Molecular Formula
C17H14O6
Molecular Weight
314.29
Precautions
H302, H315, H319, H335
References & Citations
[1]Lim H, et al. Anti-inflammatory activity of pectolinarigenin and pectolinarin isolated from Cirsium chanroenicum. Biol Pharm Bull. 2008 Nov;31 (11) :2063-7.|[2]Lee S, et al. Pectolinarigenin, an aglycone of pectolinarin, has more potent inhibitory activities on melanogenesis than pectolinarin.Biochem Biophys Res Commun. 2017 Nov 4;493 (1) :765-772.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
5-LOX; COX-2
Available Sizes
Curated Selection
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