Cimaterol (Standard)

Cimaterol (Standard) is the analytical standard of Cimaterol. This product is intended for research and analytical applications. Cimaterol (CL 263780) is a β-adrenergic agonist on energy metabolism in ob/ob mice[1]. The Kd for Cimaterol binding to the L6 β-receptor is 26 nM which is compatible with its EC50 for the stimulation of protein synthesis (approx 5 nM) [2].

Product Specifications

CAS Number

[54239-37-1]

Product Name Alternative

CL 263780 (Standard) ; (±) -2-Amino-5-[1-hydroxy-2-[ (1-methylethyl) amino]ethyl]benzonitrile (Standard)

UNSPSC

12352005

Target

Adrenergic Receptor; Reference Standards

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/cimaterol-standard.html

Smiles

N#CC1=CC(C(O)CNC(C)C)=CC=C1N

Molecular Formula

C12H17N3O

Molecular Weight

219.28

References & Citations

[1]H C Walker, et al. Effects of cimaterol, a beta-adrenergic agonist, on energy metabolism in ob/ob mice. Am J Physiol. 1988 Dec;255 (6 Pt 2) :R952-60.|[2]J M Harper, et al. The effects of beta agonists on muscle cells in culture. Domest Anim Endocrinol. 1990 Oct;7 (4) :477-84.|[3]Boimpoundi Eunice Flavie Ouali, et al. Beta-agonist drugs modulate the proliferation and differentiation of skeletal muscle cells in vitro. Biochem Biophys Rep. 2021 May 18;26:101019.|[4]W R Walker, et al. Evaluation of cimaterol for finishing swine including a drug withdrawal period. J Anim Sci. 1989 Jan;67 (1) :168-76.