Prednisone acetate

Prednisone acetate (Prednisone 21-acetate), a glucocorticoid, is an orally active Notch inhibitor. Prednisone acetate has anti-inflammatory activity and can enhance the immune response[1][2].

Product Specifications

CAS Number

[125-10-0]

Product Name Alternative

Prednisone 21-acetate

UNSPSC

12352211

Hazard Statement

H361, H373

Target

Glucocorticoid Receptor; Interleukin Related; Notch

Type

Reference compound

Related Pathways

Immunology/Inflammation; Neuronal Signaling; Stem Cell/Wnt; Vitamin D Related/Nuclear Receptor

Applications

Neuroscience-Neuromodulation

Field of Research

Cancer; Endocrinology; Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/prednisone-acetate.html

Purity

99.92

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

C[C@@]1(C2)[C@](C(COC(C)=O)=O)(O)CC[C@@]1([H])[C@]3([H])CCC4=CC(C=C[C@]4(C)[C@@]3([H])C2=O)=O

Molecular Formula

C23H28O6

Molecular Weight

400.46

Precautions

H361, H373

References & Citations

[1]Prednisolone acetate|[2]Wang Y, et al. Intragastric administration of prednisone acetate induced impairment of hippocampal long-term potentiation [J]. Brain Research, 2023, 1805: 148270.|[3]Zhou M, Qu R, Yin X, et al. Prednisone acetate modulates Th1/Th2 and Th17/Treg cell homeostasis in experimental autoimmune uveitis via orchestrating the Notch signaling pathway [J]. International Immunopharmacology, 2023, 116: 109809.