Implitapide

Implitapide (AEGR 427) is a microsomal triglyceride transfer protein (MTP) inhibitor.

Product Specifications

CAS Number

[177469-96-4]

Product Name Alternative

AEGR 427

UNSPSC

12352005

Target

Microsomal Triglyceride Transfer Protein (MTP)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/Implitapide.html

Purity

99.87

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC1=C(C2=C3C=CC=C2)C(N3CC4=CC=C([C@H](C5CCCC5)C(N[C@H](C6=CC=CC=C6)CO)=O)C=C4)=NC(C)=C1

Molecular Formula

C35H37N3O2

Molecular Weight

531.69

References & Citations

[1]Ueshima K, et al. Implitapide, a microsomal triglyceride transfer protein inhibitor, reduces progression of atherosclerosis in apolipoprotein E knockout mice fed a Western-type diet: involvement of the inhibition of postprandial triglyceride elevation. Biol Pharm Bull. 2005 Feb;28 (2) :247-52.