STING agonist-1
STING agonist-1 (G10) is human-specific STING agonist that elicits antiviral activity against emerging Alphaviruses. G10 potently blocks replication of Alphavirus species Venezuelan Equine Encephalitis Virus (VEEV) with IC90 of 24.57 μM[1].
Product Specifications
CAS Number
[702662-50-8]
Product Name Alternative
G10
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
STING; Virus Protease
Type
Reference compound
Related Pathways
Anti-infection; Immunology/Inflammation
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/STING-agonist-1.html
Purity
99.93
Solubility
DMSO : 75 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C(SCC(N2CC3=C(F)C=CC=C3Cl)=O)C2=C1)NCC4=CC=CO4
Molecular Formula
C21H16ClFN2O3S
Molecular Weight
430.88
Precautions
H302, H315, H319, H335
References & Citations
[1]Sali TM, et al. Characterization of a Novel Human-Specific STING Agonist that Elicits Antiviral Activity Against Emerging Alphaviruses. PLoS Pathog. 2015 Dec 8;11 (12) :e1005324.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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