Ginsenoside Rb1

Ginsenoside Rb1, a main constituent of the root of Panax ginseng, inhibits Na+, K+-ATPase activity with an IC50 of 6.3±1.0 μM. Ginsenoside also inhibits IRAK-1 activation and phosphorylation of NF-κB p65 .

Product Specifications

CAS Number

[41753-43-9]

Product Name Alternative

Gypenoside III

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Autophagy; HSV; IRAK; Mitophagy; Na+/K+ ATPase; NF-κB; Pregnane X Receptor (PXR)

Type

Natural Products

Related Pathways

Anti-infection; Autophagy; Immunology/Inflammation; Membrane Transporter/Ion Channel; NF-κB; Vitamin D Related/Nuclear Receptor

Applications

COVID-19-anti-virus

Field of Research

Inflammation/Immunology; Cancer

Assay Protocol

https://www.medchemexpress.com/Ginsenoside-Rb1.html

Concentration

10mM

Purity

99.75

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : ≥ 33.33 mg/mL

Smiles

C[C@@]([C@@]12C)(CC[C@@]3([H])C4(C)C)[C@@](C[C@@H](O)[C@]1([H])[C@]([C@@](CC/C=C(C)/C)(C)O[C@@H]([C@@H]([C@@H](O)[C@@H]5O)O)O[C@@H]5CO[C@@H]([C@@H]([C@@H](O)[C@@H]6O)O)O[C@@H]6CO)([H])CC2)([H])[C@]3(CC[C@@H]4O[C@@](O[C@H](CO)[C@@H](O)[C@@H]7O)([H])[C@@H]7O[C@]([C@@H]([C@@H](O)[C@@H]8O)O)([H])O[C@@H]8CO)C

Molecular Formula

C54H92O23

Molecular Weight

1109.29

Precautions

H302, H315, H319, H335

References & Citations

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

HSV-1; IRAK1; RelA/p65

Available Sizes

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