Evodiamine
Evodiamine is an alkaloid isolated from the fruit of Evodia rutaecarpa Bentham with diverse biological activities including anti-inflammatory, anti-obesity, and antitumor.
Product Specifications
CAS Number
[518-17-2]
Product Name Alternative
(+) -Evodiamine; d-Evodiamine
UNSPSC
12352005
Hazard Statement
H300
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Evodiamine.html
Concentration
10mM
Purity
99.97
Solubility
DMSO : 10 mg/mL (ultrasonic)
Smiles
O=C1C2=CC=CC=C2N(C)[C@](N1CC3)([H])C4=C3C5=CC=CC=C5N4
Molecular Formula
C19H17N3O
Molecular Weight
303.36
Precautions
H300
References & Citations
[1]Wang S, et al. Scaffold Diversity Inspired by the Natural Product Evodiamine: Discovery of Highly Potent and Multitargeting Antitumor Agents. J Med Chem. 2015 Aug 27;58 (16) :6678-96.|[2]Li RF, et al. Effects of Evodiamine on the Pharmacokinetics of Dapoxetine and Its Metabolite Desmethyl Dapoxetine inRats. Pharmacology. 2016;97 (1-2) :43-7.|[3]Shi L, et al. Evodiamine exerts anti-tumor effects against hepatocellular carcinoma through inhibiting β-catenin-mediated angiogenesis. Tumour Biol. 2016 Sep;37 (9) :12791-12803.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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