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BDM91270

BDM91270 (compound 29) is an E. coli AcrAB-TolC efflux pump inhibitor with an EC90 of 0.6 μM for wild-type E. coli AcrB. BDM91270 can be used in the study of Escherichia coli drug resistance[1].

Product Specifications

CAS Number

[2892824-11-0]

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/bdm91270.html

Purity

98.30

Solubility

DMSO : 25 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)

Smiles

ClC1=C(N2CCNCC2)N=CC(C(OC3=CC=CC(CN)=C3)=O)=C1.Cl.Cl

Molecular Formula

C17H21Cl3N4O2

Molecular Weight

419.73

References & Citations

[1]Compagne N, et al. Optimization of pyridylpiperazine-based inhibitors of the Escherichia coli AcrAB-TolC efflux pump. Eur J Med Chem. 2023 Jul 7;259:115630.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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