Methyl cholate

Methyl cholate is a methyl ester of bile acid and sterol esters that can act as supramolecular carriers for aldoses (e.g., glucose, galactose, mannose) . Methyl cholate selectively binds to aldoses to form non-covalent complexes and migrates in supported liquid membranes (SLMs), thereby facilitating the transport of sugars. Cholic acid is one of the major bile acids produced by the liver and is synthesized from cholesterol. Methyl cholate can be used to study the selective separation and transport of carbohydrates[1][2][3].

Product Specifications

CAS Number

[1448-36-8]

UNSPSC

12352211

Hazard Statement

H315, H319, H320

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/methyl-cholate.html

Concentration

10mM

Purity

99.81

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O[C@H]1[C@@]2([H])[C@@]3([H])[C@@]([C@]([C@H](C)CCC(OC)=O)([H])CC3)([C@@H](O)C[C@]2([H])[C@]4(C)[C@](C[C@H](O)CC4)([H])C1)C

Molecular Formula

C25H42O5

Molecular Weight

422.60

Precautions

H315, H319, H320

References & Citations

[1]Al-Aboudi A, et al. Biotransformation of methyl cholate by Aspergillus niger. Steroids. 2009 Apr-May;74 (4-5) :483-6.|[2]L J Bennion, et al. Effects of Oral Contraceptives on the Gallbladder Bile of Normal Women. N Engl J Med, 294 (4), 189-92 1976 Jan 22|[3]Hassoune H, et al. Mechanism of transport of sugars across a supported liquid membrane using methyl cholate as mobile carrier[J]. Desalination, 2009, 242 (1-3) : 84-95.