G3-C12 (TFA)

G3-C12 (TFA) is a galectin-3 binding peptide, with Kd of 88 nM, and shows anticancer activity.

Product Specifications

UNSPSC

12352209

Target

Galectin

Type

Peptides

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/G3-C12_TFA.html

Purity

99.44

Solubility

H2O : ≥ 50 mg/mL

Smiles

OC(C(F)(F)F)=O.O=C(N[C@@H](CC(N)=O)C(N[C@@H]([C@H](O)C)C(N1[C@@H](CCC1)C(N[C@@H](CS)C(NCC(N2[C@@H](CCC2)C(N[C@@H](CC3=CC=C(C=C3)O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC4=CNC=N4)C(N[C@@H](CC(O)=O)C(N[C@@H](CS)C(N5[C@@H](CCC5)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C)N

Molecular Formula

C74H115N23O23S2.C2HF3O2

Molecular Weight

1873.00

References & Citations

[1]Kopansky E, et al. Peptide-directed HPMA copolymer-doxorubicin conjugates as targeted therapeutics for colorectal cancer. J Drug Target. 2011 Dec;19 (10) :933-43.