Lodenafil

Lodenafil is a potent phosphodiesterase type 5 (PDE5) inhibitor for the treatment of erectile dysfunction (ED) [1].

Product Specifications

CAS Number

[139755-85-4]

Product Name Alternative

Hydroxyhomosildenafil

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Phosphodiesterase (PDE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/lodenafil.html

Purity

99.94

Solubility

DMSO : ≥ 250 mg/mL

Smiles

O=C1C2=C(NC(C3=CC(S(=O)(N4CCN(CC4)CCO)=O)=CC=C3OCC)=N1)C(CCC)=NN2C

Molecular Formula

C23H32N6O5S

Molecular Weight

504.60

Precautions

H302, H315, H319, H335

References & Citations

[1]Toque HA, et al. Pharmacological characterization of a novel phosphodiesterase type 5 (PDE5) inhibitor lodenafil carbonate on human and rabbit corpus cavernosum. Eur J Pharmacol. 2008 Sep 4;591 (1-3) :189-95.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Launched

Isoform

PDE5

Available Sizes

Curated Selection

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