N-(Phenylacetyl-d5)glycine
Product Specifications
UNSPSC Description
N-(Phenylacetyl-d5)glycine is the deuterium labeled Phenylacetylglycine. Phenylacetylglycine is a gut microbial metabolite that can activate β2AR. Phenylacetylglycine protects against cardiac injury caused by ischemia/reperfusion[1][2].
Target Antigen
Adrenergic Receptor; Apoptosis; Endogenous Metabolite
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis;GPCR/G Protein;Metabolic Enzyme/Protease;Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cardiovascular Disease
Purity
99.0
Solubility
10 mM in DMSO
Smiles
OC(CNC(CC1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])=O)=O
Molecular Weight
198.23
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.|[2]Xu X, et al. The gut microbial metabolite phenylacetylglycine protects against cardiac injury caused by ischemia/reperfusion through activating β2AR. Arch Biochem Biophys. 2021 Jan 15;697:108720.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Clinical Information
No Development Reported
CAS Number
1189920-31-7
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6176292-01 0.1 mL
UBTF (Upstream Binding Transcription Factor, RNA Polymerase I, NOR-90, UBF) (FITC)
Ask
View Details 
MBS6176292-02 5x 0.1 mL
UBTF (Upstream Binding Transcription Factor, RNA Polymerase I, NOR-90, UBF) (FITC)
Ask
View Details 