STM2120
STM2120 is a METTL3-METTL14 inhibitor with an IC50 of 64.5 μM[1].
Product Specifications
CAS Number
[2762286-04-2]
UNSPSC
12352005
Target
METTL3
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/stm2120.html
Purity
99.92
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
O=C1C=C(C(NCC2=CN3C(C)=CC=CC3=N2)=O)N=C4C=CC=CN14
Molecular Formula
C18H15N5O2
Molecular Weight
333.34
References & Citations
[1]Yankova E, et al. Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia. Nature. 2021 May;593 (7860) :597-601.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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