Lith-O-Asp
Lith-O-Asp is a sialytransferase (ST) inhibitor, with IC50s of 12-37 μM.
Product Specifications
CAS Number
[881179-02-8]
UNSPSC
12352211
Target
Sialyltransferase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Lith-O-Asp.html
Concentration
10mM
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC(O)=O)([H])[C@@]3([H])[C@]([C@@]4([C@](C[C@H](OC([C@@H](N)CC(O)=O)=O)CC4)([H])CC3)C)([H])CC1
Molecular Formula
C28H45NO6
Molecular Weight
491.66
References & Citations
[1]Chen JY, et al. A novel sialyltransferase inhibitor suppresses FAK/paxillin signaling and cancer angiogenesis and metastasis pathways. Cancer Res. 2011 Jan 15;71 (2) :473-83.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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