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(±) -Scopolamine

(±) -Scopolamine (Atroscine) is the racemic modification of Scopolamine. (±) -Scopolamine inhibits α-adrenergic receptor activity. (±) -Scopolamine has Ki values of 33 μM and 7.25 nM for α1-adrenerg receptor and muscarinic cholinergic receptor, respectively[1].

Product Specifications

CAS Number

[138-12-5]

Product Name Alternative

Atroscine

UNSPSC

12352005

Hazard Statement

H302-H312-H332

Target

Adrenergic Receptor

Type

Natural Products

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/minus-scopolamine.html

Solubility

10 mM in DMSO

Smiles

CN1[C@@H]2[C@H](O3)[C@H]3[C@H]1C[C@@H](OC(C(C4=CC=CC=C4)CO)=O)C2

Molecular Formula

C17H21NO4

Molecular Weight

303.35

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

References & Citations

[1]Cantor EH, et al. Structure-activity requirements for hypotension and alpha-adrenergic receptor blockade by analogues of atropine. Eur J Pharmacol. 1983 May 20;90 (1) :75-83.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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