Trofosfamide

Trofosfamide is an orally bioavailable oxazaphosphorine derivative with antineoplastic activity[1].

Product Specifications

CAS Number

[22089-22-1]

UNSPSC

12352005

Hazard Statement

H301, H340, H350, H360, H372, H413

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

Neuroscience-Neuromodulation

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/trofosfamide.html

Purity

99.66

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

ClCCN1P(OCCC1)(N(CCCl)CCCl)=O

Molecular Formula

C9H18Cl3N2O2P

Molecular Weight

323.58

Precautions

H301, H340, H350, H360, H372, H413

References & Citations

[1]Witte HM, et al. Trofosfamide in the treatment of elderly or frail patients with diffuse large B-cell lymphoma. J Cancer Res Clin Oncol. 2019 Jan;145 (1) :129-136.|[2]Görn M, et al. A pilot study of docetaxel and trofosfamide as second-line 'metronomic' chemotherapy in the treatment of metastatic non-small cell lung cancer (NSCLC) . Onkologie. 2008 Apr;31 (4) :185-9.