Trofosfamide
Trofosfamide is an orally bioavailable oxazaphosphorine derivative with antineoplastic activity[1].
Product Specifications
CAS Number
[22089-22-1]
UNSPSC
12352005
Hazard Statement
H301, H340, H350, H360, H372, H413
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/trofosfamide.html
Purity
99.66
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
ClCCN1P(OCCC1)(N(CCCl)CCCl)=O
Molecular Formula
C9H18Cl3N2O2P
Molecular Weight
323.58
Precautions
H301, H340, H350, H360, H372, H413
References & Citations
[1]Witte HM, et al. Trofosfamide in the treatment of elderly or frail patients with diffuse large B-cell lymphoma. J Cancer Res Clin Oncol. 2019 Jan;145 (1) :129-136.|[2]Görn M, et al. A pilot study of docetaxel and trofosfamide as second-line 'metronomic' chemotherapy in the treatment of metastatic non-small cell lung cancer (NSCLC) . Onkologie. 2008 Apr;31 (4) :185-9.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
Curated Selection
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