CALP3
CALP3, a Ca2+-like peptide, is a potent Ca2+ channel blocker that activates EF hand motifs of Ca2+-binding proteins. CALP3 can functionally mimic increased [Ca2+]i by modulating the activity of Calmodulin (CaM), Ca2+ channels and pumps. CALP3 has the potential in controlling apoptosis in diseases such as AIDS or neuronal loss due to ischemia[1][2].
Product Specifications
CAS Number
[261969-05-5]
UNSPSC
12352209
Hazard Statement
H302, H315, H319
Target
Calcium Channel
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/calp3.html
Purity
99.55
Solubility
DMSO : 12.5 mg/mL (ultrasonic)
Smiles
O=C([C@@H](N)C(C)C)N[C@@H](CCCCN)C(N[C@H](C(NCC(N[C@@H](C(C)C)C(NCC(N[C@H](C(N[C@H](C(O)=O)CCCCN)=O)CC1=CC=CC=C1)=O)=O)=O)=O)CC2=CC=CC=C2)=O
Molecular Formula
C44H68N10O9
Molecular Weight
881.07
Precautions
H302, H315, H319
References & Citations
2+
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
Calcium Channel
Available Sizes
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