TCB2
TCB2 is an agonist of serotonin 5-HT2A receptor.
Product Specifications
CAS Number
[912342-28-0]
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/TCB2.html
Purity
99.21
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 25 mg/mL (ultrasonic)
Smiles
NCC1C2=C(OC)C=C(Br)C(OC)=C2C1.[H]Br
Molecular Formula
C11H15Br2NO2
Molecular Weight
353.05
References & Citations
[1]Fox MA, et al. The serotonin 5-HT (2A) receptor agonist TCB-2: a behavioral and neurophysiological analysis. Psychopharmacology (Berl) . 2010 Sep;212 (1) :13-23.|[2]Dasiel O. Borroto-Escuela, et al. Existence of Brain 5-HT1A–5-HT2A Isoreceptor Complexes with Antagonistic Allosteric Receptor–Receptor Interactions Regulating 5-HT1A Receptor Recognition. ACS Omega. 2017 Aug 31; 2 (8) : 4779–4789.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor; α-1 microglobulin
Available Sizes
Curated Selection
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