DMS-612

DMS-612 (NSC-281612) is an alkylating agent with anti-renal cell carcinoma activity. DMS-612 can be used in cancer research[1].

Product Specifications

CAS Number

[56967-08-9]

Product Name Alternative

NSC-281612

UNSPSC

12352005

Target

DNA Alkylator/Crosslinker

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/dms-612.html

Solubility

10 mM in DMSO

Smiles

O=CC1=CC=C(N(CCOS(=O)(C)=O)CCOS(=O)(C)=O)C=C1C

Molecular Formula

C14H21NO7S2

Molecular Weight

379.45

References & Citations

[1]Parise RA, et al. Formation of active products of benzaldehyde dimethane sulfonate (NSC 281612, DMS612) in human blood and plasma and their activity against renal cell carcinoma lines. Cancer Chemother Pharmacol. 2013 Jan;71 (1) :73-83. doi: 10.1007/s00280-012-1980-1. Epub 2012 Oct 5.