4β-Hydroxycholesterol

4β-hydroxy Cholesterol is a major oxysterol cholesterol metabolite and a precursor in the synthesis of bile acids that is found in human circulation[1].

Product Specifications

CAS Number

[17320-10-4]

UNSPSC

12352211

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/4β-hydroxycholesterol.html

Purity

99.96

Solubility

DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C) |Ethanol : 16.67 mg/mL (ultrasonic)

Smiles

O[C@@H](CC[C@]1(C2=CC[C@@]3([C@@]1(CC[C@]4([C@]3(CC[C@@]4([C@@H](CCCC(C)C)C)[H])[H])C)[H])[H])C)[C@@H]2O

Molecular Formula

C27H46O2

Molecular Weight

402.65

References & Citations

[1]Granchi C, Rizzolio F, Bordoni V, Caligiuri I, Manera C, Macchia M, Minutolo F, Martinelli A, Giordano A, Tuccinardi T. 4-Aryliden-2-methyloxazol-5 (4H) -one as a new scaffold for selective reversible MAGL inhibitors. J Enzyme Inhib Med Chem. 2016;31 (1) :137-46.