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Pyruvic acid

Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats.

Product Specifications

CAS Number

[127-17-3]

Product Name Alternative

Acetylformic acid

UNSPSC

12352211

Hazard Statement

H227, H314

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/Pyruvic_acid.html

Purity

99.86

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

CC(C(O)=O)=O

Molecular Formula

C3H4O3

Molecular Weight

88.06

Precautions

H227, H314

References & Citations

[1]Kładna A, et al. Reactivity of pyruvic acid and its derivatives towards reactive oxygen species. Luminescence. 2015 Nov;30 (7) :1153-8.|[2]Liu G, et al. Role of pyruvic acid in osteoclast differentiation[J]. Chinese Journal of Tissue Engineering Research, 2023, 27 (31) : 5015.|[3]Tanaka KI, et al., Pyruvic acid prevents Cu2+/Zn2+-induced neurotoxicity by suppressing mitochondrial injury. Biochem Biophys Res Commun. 2018 Jan 1;495 (1) :1335-1341. |[4]Mazzio EA, et al., Cytoprotection of pyruvic acid and reduced beta-nicotinamide adenine dinucleotide against hydrogen peroxide toxicity in neuroblastoma cells. Neurochem Res. 2003 May;28 (5) :733-41.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, stored under nitrogen)

Scientific Category

Natural Products

Clinical Information

Launched

Isoform

Human Endogenous Metabolite; Microbial Metabolite

Citation 01

Adv Sci (Weinh) . 2024 Jul 9:e2406333.|Cell Death Dis. 2023 Apr 6;14 (4) :246.|Cell Prolif. 2023 Sep;56 (9) :e13442.|J Virol. 2024 Mar 19;98 (3) :e0175123.|Redox Biol. 2024 May:71:103112.|ACS Nano. 2024 Aug 20;18 (33) :21855-21872.|bioRxiv. 2025 Aug 22.|Cancer Commun (Lond) . 2025 May 29.|Cell Biochem Biophys. 2025 Mar;83 (1) :879-891.|Int Immunopharmacol. 2023 Jul:120:110292.|J Agric Food Chem. 2025 Aug 13;73 (32) :20385-20395.|J Hypertens. 2024 Apr 23.|Toxicology. 2025 Oct 13:519:154309.

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