6-Bnz-cAMP

6-Bnz-cAMP (N6-Benzoyl-cAMP), a derivative of cyclic adenosine monophosphate (cAMP), is a potent inhibitor of the bTREK-1 potassium channel. 6-Bnz-cAMP can strongly inhibit the bTREK-1 potassium channel through a protein kinase A (PKA) independent mechanism. 6-Bnz-cAMP can be used to explore potential signal transduction proteins in the cAMP signaling pathway[1].

Product Specifications

CAS Number

[30275-80-0]

Product Name Alternative

N6-Benzoyl-cAMP

UNSPSC

12352005

Target

Potassium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/6-bnz-camp.html

Smiles

O[C@@H]1[C@H](OP2(O)=O)[C@@H](CO2)O[C@H]1N3C=NC4=C3N=CN=C4NC(C5=CC=CC=C5)=O

Molecular Formula

C17H16N5O7P

Molecular Weight

433.31

References & Citations

[1]Liu H, et al. N6-substituted cAMP analogs inhibit bTREK-1 K+ channels and stimulate cortisol secretion by a protein kinase A-independent mechanism[J]. Molecular pharmacology, 2009, 76 (6) : 1290-1301.